Carbamic acid, N-[1-(hydroxymethyl)propyl]-, phenylmethyl ester
(RS)-benzyl (1-hydroxybutan-2-yl)carbamate
CAS: 137160-74-8
Molecular Formula: C12H17NO3
Carbamic acid, N-[1-(hydroxymethyl)propyl]-, phenylmethyl ester - Names and Identifiers
Carbamic acid, N-[1-(hydroxymethyl)propyl]-, phenylmethyl ester - Physico-chemical Properties
| Molecular Formula | C12H17NO3 |
| Molar Mass | 223.27 |
| Density | 1.125±0.06 g/cm3(Predicted) |
| Boling Point | 386.5±35.0 °C(Predicted) |
| pKa | 11.90±0.46(Predicted) |
Carbamic acid, N-[1-(hydroxymethyl)propyl]-, phenylmethyl ester - Introduction
N-Cbz-2-Amino-l-butanol is an organic compound whose chemical formula is C19H25NO2. It has the following properties:
1. Appearance: N-Cbz-2-amino -1-butanol is a white crystalline solid.
2. solubility: soluble in most organic solvents, such as ethanol, acetone, insoluble in water.
3. use: N-Cbz-2-amino -1-butanol commonly used in organic synthesis reaction as a protecting group. It can protect some sensitive functional groups to prevent them from unnecessary reactions in chemical reactions. It has a wide range of applications in the synthesis of drugs, bioactive substances and so on.
4. Preparation method: The preparation of N-Cbz-2-amino -1-butanol can be carried out by the following steps:
-First, 2-amino-1-butanol is reacted with 1-(benzoyl) imidazole (Cbz-Cl) to generate N-Cbz-2-amino-1-butanol.
-This reaction is usually carried out under an inert atmosphere and stirred at room temperature for several hours until the reaction is complete.
-After completion of the reaction, the product is purified by steps of crystallization, washing, etc.
5. safety information: N-Cbz-2-amino -1-butanol specific safety information and use precautions need to be determined according to the specific experimental situation. During use, necessary laboratory safety measures should be taken, including wearing appropriate protective gloves, glasses and other equipment, and maintaining good ventilation conditions. In addition, direct skin contact and inhalation of its dust should be avoided. In case of accidental contact, rinse immediately with plenty of water. In a laboratory environment, follow the relevant safety procedures and operating instructions.
1. Appearance: N-Cbz-2-amino -1-butanol is a white crystalline solid.
2. solubility: soluble in most organic solvents, such as ethanol, acetone, insoluble in water.
3. use: N-Cbz-2-amino -1-butanol commonly used in organic synthesis reaction as a protecting group. It can protect some sensitive functional groups to prevent them from unnecessary reactions in chemical reactions. It has a wide range of applications in the synthesis of drugs, bioactive substances and so on.
4. Preparation method: The preparation of N-Cbz-2-amino -1-butanol can be carried out by the following steps:
-First, 2-amino-1-butanol is reacted with 1-(benzoyl) imidazole (Cbz-Cl) to generate N-Cbz-2-amino-1-butanol.
-This reaction is usually carried out under an inert atmosphere and stirred at room temperature for several hours until the reaction is complete.
-After completion of the reaction, the product is purified by steps of crystallization, washing, etc.
5. safety information: N-Cbz-2-amino -1-butanol specific safety information and use precautions need to be determined according to the specific experimental situation. During use, necessary laboratory safety measures should be taken, including wearing appropriate protective gloves, glasses and other equipment, and maintaining good ventilation conditions. In addition, direct skin contact and inhalation of its dust should be avoided. In case of accidental contact, rinse immediately with plenty of water. In a laboratory environment, follow the relevant safety procedures and operating instructions.
Last Update：2024-04-09 21:01:54
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